MISMS researchers analyzed fine-grain insurance claims data on influenza-like-illnesses over eight seasons in ~300 locations throughout the United States. Using statistical methods, they found that seven of eight epidemics likely originated in the Southern US, that influenza spatial transmission is dominated by local traffic between cities, and that seasons marked by novel influenza virus circulation had a particularly radial, localized spatial structure. The findings are in stark contrast to prevailing theories of influenza spatial transmission that suggest that transmission is favored in low humidity environments and that spread is a dominated by air traffic between populous hubs. The findings are published in PLoS Computational Biology.
6th ANISE (African Network for Influenza Surveillance and Epidemiology) Meeting
November 13 to 17, 2017
at Hotel Carlton
Please register and submit your abstract on-line (due August 15) to the meeting website: www.anise-network.org
The agenda is in progress, but we plan to hold plenary sessions from November 13- 15 and training workshops November 16-17.
Big data derived from electronic health records, social media, the internet and other digital sources have the potential to provide more timely and detailed information on infectious disease threats or outbreaks than traditional surveillance methods. A team of scientists led by MISMS researchers Cecile Viboud and Gerardo Chowell reviewed the growing body of research on the subject and has published its analyses in a special issue of Journal of Infectious Diseases.
Last week, the work of Dr Andrew Bowman, Ohio State University, was highlighted in Yahoo news. Dr Bowman has been tracking influenza viruses in US exhibition swine since 2009. In 2016, Dr Bowman co-authored two studies with MISMS researchers examining how novel viruses with pandemic potential evolve in exhibition swine. One study, published in January 2016 in the Journal of Infectious Diseases, identified the active role of exhibition swine in the evolution of novel variant viruses that have infected over 300 humans in the United States since 2011. A second study, published online in September 2016 in the Journal of Virology, traces long-term evolutionary trends of influenza viruses in exhibition swine and demonstrates how these can be used to predict outbreaks of variant swine viruses in humans.
Researchers from the Fogarty International Center, Icahn School of Medicine at Mount Sinai, and Laboratorio Avi-Mex have used genetic sequencing to show that the 2009 global H1N1 influenza pandemic began in central Mexico, originating in pigs and spreading to humans. Mexico is not typically considered a source of novel influenza strains, and the findings demonstrate how long-distance trade of live swine can move viruses between continents and regions to generate novel reassortant viruses. The new findings appear online in the journal eLIFE.