MISMS: a global collaboration to study influenza
- 18-year program to advance evidence-based policies for influenza control in the US and globally
- Includes basic research and training workshops led by a core team of scientists at Fogarty International Center (FIC), based at the US National Institutes of Health.
- MISMS staff annually organize training workshops to teach methods of data analysis, including time-series, modeling, and phylogenetic analysis
- Develops global collaborations to facilitate data-sharing and large-scale studies of disease dynamics
- Focus on low- and middle-income countries
MISMS training workshop in South Africa, 2018
Examples of how MISMS research impacted policy decision-making:
Improving influenza vaccination strategies during pandemics based on the age-shift from elderly to younger adults
Seasonal influenza vaccine campaigns in children, who are key vectors of transmission in communities, can provide indirect protection to vulnerable seniors with low immune responses to vaccination and high mortality.
Advising countries in tropical and sub-tropical regions on whether to use the Northern hemisphere or Southern hemisphere vaccine formulation, based on the seasonal timing of their influenza epidemics, which tends to be more variable than the winter epidemics seen in temperate regions.
Recognizing role of humans in transmitting influenza viruses to animals (reverse zoonosis), including transmission of pandemic H1N1 viruses from humans to swine and to zoo animals.
Timing of waves of previous pandemics, NEJM 2009